肝脏修复博士职位
PhD Precision Repair of Donor Livers During Machine Perfusion
原帖优先：申请材料、截止时间与资格以原帖和学校官方说明为准。
AI 中文速览
- 研究内容
- 开发和评估创新策略以检测、预防和修复高风险捐献肝脏的氧化应激相关损伤
- 申请条件
- 原文未说明
- 待遇
- 薪资 EUR 3217 每月
- 申请方式
- 原文未说明
- 材料清单
- 原文未说明
由 @cf/meta/llama-3.3-70b-instruct-fp8-fast 生成，博士岗判定置信度 100%。
结构化信息
- 截止
- （Europe/Amsterdam） 剩 6 天
- 学科
- 材料科学
- 合同类型
- 雇佣合同
- 原文薪资
- EUR 3,217 / 月（税前）
- 税后月薪（估）
- ¥19,100；房租后 ¥11,200
- 估算假设
- 单身、无子女、雇佣合同的粗略估算，以学校 offer 为准；扣除率 25%；汇率日期 2026-10-01
- 原帖发布
- 本站收录
- 内容更新
- 来源
- AcademicTransfer（荷兰学术招聘） · 最近核对 2026-10-07
判定依据（原文摘录）
- is_phd
This PhD project
原文
Make more donor livers transplantable through cutting-edge transplantation research
Improving the quality and availability of donor organs is one of the greatest challenges in modern transplantation. At the University of Groningen and UMCG, you will contribute to the development of next-generation technologies aimed at assessing, protecting, and repairing donor livers before transplantation. This PhD project is embedded within the multidisciplinary CRISPR-CRYSTAL consortium, bringing together experts in transplantation, nanotechnology, quantum sensing, mitochondrial medicine, and epigenetic editing. The project combines fundamental science with a clear path toward clinical translation, offering the opportunity to make a direct impact on patient care.
About your role
During machine perfusion, donor livers can be maintained outside the body, creating a unique opportunity to assess organ quality and deliver targeted therapies before transplantation. In this PhD project, you will develop and evaluate innovative strategies to detect, prevent, and repair oxidative stress–associated injury in high-risk donor livers.
The project integrates three complementary approaches:
- real-time quantum nanodiamond sensing of oxidative stress;
- mitochondrial protection using the clinical-stage compound SUL-238;
- CRISPR-based epigenetic editing delivered via lipid nanoparticles;
Using a combination of cell models and human donor livers, you will investigate how these technologies can improve organ quality and increase the number of transplantable donor livers.
Your main responsibilities
- Performing (long-term) ex vivo liver perfusion experiments using hypothermic and normothermic machine perfusion platforms.
- Evaluating mitochondrial function, oxidative stress, and liver viability during perfusion.
- Testing nanoparticle-based delivery systems and CRISPR-based epigenetic therapies.
- Analyzing and interpreting experimental data and presenting findings at scientific meetings.
- Collaborating closely with academic and industrial consortium partners.
- Contributing to scientific publications and ensuring that the research results in a PhD thesis.