EPIC项目生物膜与抗菌纳米载体方向博士研究员
PhD Candidate EPIC Project
原帖优先：申请材料、截止时间与资格以原帖和学校官方说明为准。
AI 中文速览
- 研究内容
- 研究新型内溶素制剂的抗菌效力、抗生物膜活性、生物安全性以及宿主相容性；评估其对浮游及生物膜相关金黄色葡萄球菌和表皮葡萄球菌（包括MRSA）的活性，开发先进的体外生物膜和感染模型（如微流控系统）；评估细胞毒性、免疫反应及对骨相关细胞的影响。
- 申请条件
- 原文未说明具体学位或专业背景要求，但明确招募博士生候选人并要求开展相关实验研究。
- 待遇
- 月薪为 EUR 3204 至 4051。
- 申请方式
- 原文未说明具体的申请方式、提交地址及截止日期。
由 gemini-2.5-flash-lite 生成，博士岗判定置信度 100%。
岗位信息
- 截止
- （Europe/Amsterdam） 剩 25 天
- 学科
- 生命科学
- 合同类型
- 雇佣合同
- 原文薪资
- EUR 3,204–4,051 / 月（税前）
- 税后月薪（估）
- ¥19,000–¥24,000；房租后 ¥11,100–¥16,100
- 估算假设
- 单身、无子女、雇佣合同的粗略估算，以学校 offer 为准；扣除率 25%；汇率日期 2026-10-01
- 原帖发布
- 本站收录
- 内容更新
- 原帖导师候选（待核验）
- Prof. dr. Bastiaan Krom, Prof. dr. Astrid Bakker, dr. ing. Michel Hoogenkamp, dr. Jianfeng Jin
- 来源
- AcademicTransfer（荷兰学术招聘） · 最近核对 2026-10-21
- 详情核验
判定依据（原文摘录）
- 这是一项博士培养机会
We seek a highly motivated PhD candidate to investigate the antimicrobial efficacy, anti-biofilm activity, biosafety, and host compatibility of novel endolysin formulations.
原文
Project overview
Antimicrobial resistance (AMR) is a major healthcare challenge. Prosthetic joint infections, often caused by Staphylococcus aureus and Staphylococcus epidermidis , are difficult to treat because these bacteria form biofilms that protect them from antibiotics and host defenses.
Within the NWO-funded EPIC (Endolysin-based Protective Implant nanoCarriers) consortium, ACTA, the University of Twente, Micreos, LipoCoat, and clinical partners are developing innovative endolysin-loaded nanocarriers to prevent and treat implant-associated infections.
We seek a highly motivated PhD candidate to investigate the antimicrobial efficacy, anti-biofilm activity, biosafety, and host compatibility of novel endolysin formulations.
Your role
You will: • Investigate the antimicrobial efficacy and biosafety of endolysin-based formulations • Evaluate activity against planktonic and biofilm-associated S. aureus and S. epidermidis , including MRSA • Develop advanced in vitro biofilm and infection models, including microfluidic systems • Assess activity against intracellular staphylococci and monitor resistance development • Evaluate cytotoxicity, immune responses, and effects on bone-related cells using human cell culture and 3D tissue models • Collaborate with academic and industrial consortium partners • Publish findings in peer-reviewed journals and present at scientific conferences
You will be based in both the Department of Preventive Dentistry and the Department of Oral Cell Biology at ACTA and work in an interdisciplinary environment spanning microbiology, cell biology, biomaterials, and host-microbe interactions.
The supervisory team consists of Prof. dr. Bastiaan Krom, Prof. dr. Astrid Bakker, dr. ing. Michel Hoogenkamp, and dr. Jianfeng Jin.