利用疟原虫蛋白质降解机制对抗疟原虫博士研究员
PhD Studentship: Turning the Malaria Parasite's Protein Degradation Machinery Against It
原帖优先：申请材料、截止时间与资格以原帖和学校官方说明为准。
AI 中文速览
- 研究内容
- 本项目旨在探索一种完全不同的杀灭疟原虫的方法，即利用其自身的蛋白质降解机制选择性破坏其生存所需的蛋白质，结合寄生虫遗传学、生物化学和化学生物学开发操纵蛋白质稳定性的新方法。
- 申请条件
- 申请人应持有（或预计获得）相关专业本科荣誉学位或硕士学位的英国二级甲等（Upper 2.1）或更高同等学历，且仅限符合英国本地学费（Home fees）资格的申请人。
- 待遇
- 全额资助的博士生奖学金，涵盖当前研究委员会标准的学生生活津贴（stipend）以及英国本地大学学费（Home University Fees），资助期限为4年，自2027年10月起。
- 申请方式
- 所有申请须通过剑桥大学申请者门户网站在线提交，申请病理学博士项目（BLPA22），截止日期为2026年12月2日，申请时须注明参考编号 PK49372 或 PK51394。
- 材料清单
- 2份学术推荐信（必需，须在截止日期前由推荐人提交）
- 动机信/说明（阐述申请该领域的动机、研究兴趣、背景以及将带来的素质和经验）
由 gemini-2.5-flash-lite 生成，博士岗判定置信度 100%。
岗位信息
- 截止
- （Europe/London） 剩 42 天
- 学科
- 生命科学
- 合同类型
- 雇佣合同
- 原帖发布
- 本站收录
- 内容更新
- 原帖导师候选（待核验）
- Katerina Artavanis-Tsakonas, Laura Itzhaki
- 来源
- jobs.ac.uk（英国博士项目及学术招聘） · 最近核对 2026-10-20
- 详情核验
判定依据（原文摘录）
- is_phd
All applications should be made online via the University's Applicant Portal for a PhD in Pathology (BLPA22)
- bachelor_ok
Applicants should hold (or expect to obtain) the equivalent of a UK upper 2.1 or higher in an undergraduate honours or Masters degree in a relevant subject.
- eligibility_labels
The studentships are available to students who qualify for UK HOME FEES ONLY .
原文
Location: Central Cambridge
Project Title: Turning the Malaria Parasite's Protein Degradation Machinery Against It - Professor Katerina Artavanis-Tsakonas, co-supervised with Laura Itzhaki (Department of Pharmacology)
Malaria remains a major global health challenge, with drug resistance threatening the effectiveness of existing treatments. This project will explore a fundamentally different way to kill malaria parasites: harnessing their own protein-degradation machinery to selectively destroy proteins they need to survive. Our lab studies how the ubiquitin system works in Plasmodium falciparum, revealing important differences between parasite and human cells that could be exploited therapeutically. This project will combine parasite genetics, biochemistry and chemical biology to develop new ways of manipulating protein stability. The aim is to create powerful tools for discovering new parasite biology while exploring novel strategies for antimalarial drug development.
The Department of Pathology has an excellent reputation in pure biological and biomedical research and is offering fully funded* studentships from October 2027 to work with one of the Research Group Leaders in this large and vibrant Department.
All applications should be made online via the University's Applicant Portal for a PhD in Pathology (BLPA22) via the above ‘ Apply ’ button. A completed application must be submitted by the closing date below. An application is only complete when all supporting documents, including the 2 academic references, are submitted.
It is the applicant's responsibility to ensure their referees submit their references before the closing date of the studentship.
The studentships are available to students who qualify for UK HOME FEES ONLY .
Please check for eligibility details using this website: https://www.postgraduate.study.cam.ac.uk/finance/fees/what-my-fee-status
Funding will cover the student's stipend at the current Research Council rate and Home University Fees. The studentship will be funded for 4 years from October 2027.
Applicants should hold (or expect to obtain) the equivalent of a UK upper 2.1 or higher in an undergraduate honours or Masters degree in a relevant subject. The studentship is open to those eligible for the Home rate of University fees. Additionally, the Department requires that by the time of interview all potential students must have fulfilled the language requirements for admission. ( http://www.graduate.study.cam.ac.uk/courses/directory/blpapdpth/requirements )
Please also explain your motivation why you wish to pursue a PhD in this area, outline your research interests and background, and describe the qualities and experience you will bring to the role.
Applications from ineligible candidates will not be considered.
Further information about the course can be found on our website.
Closing date: 2nd December 2026
Please quote reference PK49372 on your application and in any correspondence about this vacancy.
Please quote reference PK51394 on your application and in any correspondence about this vacancy.
The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.
The University has a responsibility to ensure that all employees are eligible to live and work in the UK.
Funding will cover the student's stipend at the current Research Council rate and Home University Fees.