小RNA,大影响:SNORD116在脂肪细胞代谢发育中的作用博士研究员

PhD Studentship: Small RNA, Big Impact: The role of SNORD116 in the metabolic development of adipocytes

The University of East Anglia · 英国 · Norwich

原帖优先:申请材料、截止时间与资格以原帖和学校官方说明为准。

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研究内容
本项目旨在研究RNA生物学中一个新兴且相对探索不足的领域,即小核仁RNA(snoRNAs)在调节脂肪细胞代谢发育中的作用。成功入选者将利用先进的基因编辑多能干细胞,研究snoRNAs如何影响脂肪细胞代谢背后的机制。
申请条件
原文未说明具体学位或专业要求,仅提及适合寻求培养尖端分子和细胞技术专业知识的学生。
待遇
提供为期4年的Norwich Research Park Biosciences Doctoral Training Partnership PhD DTP奖学金,包括直接支付给大学的学费、用于生活费的津贴(2026/27年度津贴标准为每年21,805英镑),以及每年5,000英镑的研究培训支持补助金(RTSG)。
申请方式
原文未说明具体的申请方式、提交语言或在线申请地址,请参考Norwich Research Park Biosciences DTP的官方申请渠道。

由 gemini-2.5-flash-lite 生成,博士岗判定置信度 100%。

岗位信息

截止
(Europe/London) 剩 37 天
学科
生物化学、遗传与分子生物学
合同类型
雇佣合同
原文薪资
GBP 21,805 / 年(税前)
税后月薪(估)
¥13,700;房租后 ¥5,400
估算假设
单身、无子女、雇佣合同的粗略估算,以学校 offer 为准;扣除率 18%;汇率日期 2026-10-01
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来源
jobs.ac.uk(英国博士项目及学术招聘) · 最近核对 2026-10-23
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判定依据(原文摘录)
  • 这是一项博士培养机会
    This project is awarded with a 4-year Norwich Research Park Biosciences Doctoral Training Partnership PhD DTP studentship.
原文

Investigating the Molecular Basis of Adipocyte Metabolic Development

Understanding how fat cells (adipocytes) develop is fundamental to population-level metabolic health. This project offers the opportunity to investigate an emerging and relatively underexplored area of RNA biology: the role of small nucleolar RNAs (snoRNAs) in regulating adipocyte metabolic development.

Once considered functionally peripheral, snoRNAs are increasingly recognised as important regulators of RNA processing and gene expression. However, their specific contribution to metabolic development remains poorly understood. This project will address that gap, providing genuine scope to generate novel insights in the field.

Using state-of-the-art gene-edited pluripotent stem cells, the successful candidate will examine how snoRNAs influence the mechanisms underlying adipocyte metabolism. The project offers comprehensive training in a range of advanced techniques, including:

• Stem cell biology and directed differentiation

• Advanced flow cytometry and single-cell sorting

• Metabolomics

• Long-read RNA sequencing

In addition to this specialist training, students will benefit from high-quality instruction in broader scientific and transferable skills, alongside access to a wide range of seminars and professional development opportunities.

The project will be based in the Smith Lab at the Bob Champion Research and Education Building, Norwich Medical School, University of East Anglia, within a collaborative and supportive environment.

This project is well suited to students seeking to develop expertise in cutting-edge molecular and cellular techniques while contributing to a growing area of metabolic research with significant relevance to human health.

Additional Funding Information

This project is awarded with a 4-year Norwich Research Park Biosciences Doctoral Training Partnership PhD DTP studentship. The studentship includes payment of tuition fees (directly to the University), a stipend to cover living expenses (2026/27 stipend rate: £21,805, and a Research Training Support Grant of £5,000 pa for each year of the studentship.

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