工程化作物抗病性以克服生长与防御权衡的博士研究员
PhD Studentship: Engineering Fitness in Disease-Resistant Crops
原帖优先：申请材料、截止时间与资格以原帖和学校官方说明为准。
AI 中文速览
- 研究内容
- 该博士项目旨在研究是否可以通过精确控制抗性基因的表达时间和位置，利用工程生物学来克服作物高产与抗病之间的生长-防御权衡。研究重点是马铃薯孢囊线虫的抗性，将大豆的抗性基因座 Rhg1 构建并测试调控部件库，以重新设计 Rhg1 构建体并评估工程植物的抗病性、根系结构和块茎产量。
- 申请条件
- 原文未说明具体的学位或专业要求，仅提及将加入 Norwich Research Park Biosciences Doctoral Training Partnership 并获得相关培训。
- 待遇
- 提供为期4年的 Norwich Research Park Biosciences Doctoral Training Partnership 博士生奖学金。奖学金包括直接支付给大学的学费、用于支付生活费用的津贴（2026/27年度津贴标准为每年21,805英镑），以及每年5,000英镑的研究培训支持金（RTSG）。
- 申请方式
- 原文未说明具体的申请方式、截止日期或提交地址。
由 gemini-2.5-flash-lite 生成，博士岗判定置信度 100%。
岗位信息
- 截止
- （Europe/London） 剩 37 天
- 学科
- 农业与生物科学
- 合同类型
- 雇佣合同
- 原文薪资
- GBP 21,805 / 年（税前）
- 税后月薪（估）
- ¥13,700；房租后 ¥5,400
- 估算假设
- 单身、无子女、雇佣合同的粗略估算，以学校 offer 为准；扣除率 18%；汇率日期 2026-10-01
- 原帖发布
- 本站收录
- 内容更新
- 来源
- jobs.ac.uk（英国博士项目及学术招聘） · 最近核对 2026-10-23
- 详情核验
判定依据（原文摘录）
- 这是一项博士培养机会
This PhD will investigate whether engineering biology can overcome this trade-off by precisely controlling when and where resistance genes are expressed.
- 项目提供奖学金及生活津贴
The studentship includes payment of tuition fees (directly to the University), a stipend to cover living expenses (2026/27 stipend rate: £21,805, and a Research Training Support Grant of £5,000pa for each year of the studentship.
原文
Engineering crop disease resistance to overcome the growth-defence trade-off
Developing crops that are both productive and resillient is one of the major challenges facing agriculture. While disease-resistance genes can protect plants from devastating pathogens, they often come with a hidden cost: reduced growth and lower yields. This PhD will investigate whether engineering biology can overcome this trade-off by precisely controlling when and where resistance genes are expressed.
You will study resistance to potato cyst nematodes, one of the UK's most important pests. A resistance locus from soybean, Rhg1, can protect against these nematodes, but continuous expression also reduces root growth and tuber yield.
We hypothesise that these impacts result from uncontrolled expression in the wrong tissues or at the wrong time, and that programmable expression could maintain resistance while avoiding these growth and yield costs.
Using world-class automation robotics in the Earlham Biofoundry, you will build and test a regulatory-part library, before applying these tools to redesign Rhg1 constructs and evaluate engineered plants for disease resistance, root architecture and tuber yield.
This highly collaborative PhD brings together engineering biology and laboratory automation expertise from the Grandellis Group at Earlham Institute, with the Witek Group at 2Blades - internationally recognised for research into genetic resistance to crop diseases.
Throughout the project, you will gain training in plant molecular biology, synthetic and engineering biology, automated DNA assembly, Biofoundry technologies, and genetic engineering These highly transferable skills are increasingly sought after in both academic research and the biotechnology sector.
The project will be conducted at the Earlham Institute, a world-class BBSRC research centre of excellence in genomics, engineering and computational biology, and AI. You will join a highly collaborative and supportive research community and have access to training and career development opportunities across the Norwich Research Park through the Norwich Research Park Biosciences Doctoral Training Partnership.
This project is awarded with a 4-year Norwich Research Park Biosciences Doctoral Training Partnership PhD DTP studentship. The studentship includes payment of tuition fees (directly to the University), a stipend to cover living expenses (2026/27 stipend rate: £21,805, and a Research Training Support Grant of £5,000pa for each year of the studentship.