心脏定位系统:心脏祖细胞如何寻路?博士研究员

PhD Studentship: The Cardiac Positioning System – How Do Heart Progenitors Find Their Way?

The University of East Anglia · 英国 · Norwich

原帖优先:申请材料、截止时间与资格以原帖和学校官方说明为准。

AI 中文速览

研究内容
本项目利用活细胞成像追踪心脏祖细胞在胚胎心脏区迁移的过程,研究指导其迁移的细胞信号和分子机制。实验中将使用分子生物学技术克隆候选基因进行错误表达,或通过CRISPR/Cas9敲低迁移中细胞的基因,绘制受干扰的迁移轨迹,以揭示特定基因产物如何影响心脏形成过程中的细胞迁移和命运决定。
申请条件
申请人需具备英国同等学力荣誉学士学位(一等或二等一级,即 Bachelors (Honours) 2:1)。英语语言要求需满足理学院同等标准(雅思总分 6.5、各单项不低于 6)。
待遇
提供 4 年期 Norwich Research Park Biosciences Doctoral Training Partnership (NRPDTP) 博士奖学金。奖学金包含学费全免、生活津贴(2026/27 学年生活津贴标准为每年 21,805 英镑),以及每年 5,000 英镑的研究培训支持补助金(RTSG)。
申请方式
原文未说明具体的网申地址或提交系统。入围申请人将在 2027 年 2 月 2 日、3 日和 4 日接受面试。如需了解更多信息,可联系 a.munsterberg@uea.ac.uk 或 t.grocott@uea.ac.uk。
材料清单
  • 个人陈述(Personal statement,须使用NRPDTP网站提供的定制模板)
  • 研究陈述(Research statement,须使用NRPDTP网站提供的定制模板)

由 gemini-2.5-flash-lite 生成,博士岗判定置信度 100%。

岗位信息

截止
(Europe/London) 剩 37 天
学科
生命科学
合同类型
雇佣合同
原文薪资
GBP 21,805 / 年(税前)
税后月薪(估)
¥13,700;房租后 ¥5,400
估算假设
单身、无子女、雇佣合同的粗略估算,以学校 offer 为准;扣除率 18%;汇率日期 2026-10-01
原帖发布
本站收录
内容更新
原帖导师候选(待核验)
Andrea Munsterberg, Tim Grocott, James Mccoll
来源
jobs.ac.uk(英国博士项目及学术招聘) · 最近核对 2026-10-23
详情核验
判定依据(原文摘录)
  • 允许学士学位申请
    At least UK equivalence Bachelors (Honours) 2:1.
  • 英语要求
    English Language requirement (Faculty of Science equivalent: IELTS 6.5 overall, 6 in each category).
原文

Primary Supervisor - Professor Andrea Munsterberg

The first organ to develop in vertebrate embryos is the heart, when two streams of cardiac progenitor cells undertake an epic migration before reuniting at the heart field – the site of future heart formation. How do cardiac progenitors achieve this feat? What clues guide them along the way and how do they “read” them?

In this exciting PhD project, you will use live cell imaging to track migration of cardiac progenitor cells as they navigate towards the embryonic heart field. You will learn molecular functional approaches to identify the cellular apparatus used by these remarkable cells to interpret a complex cell signalling landscape.

Experimentally, you will gain skills in molecular biology to clone candidate genes for mis-expression, or knock them down using CRISPR/Cas9 approaches in migrating cardiac progenitors and map their perturbed migration trajectories. This will reveal how specific gene products influence cell migration and fate decisions during heart formation.

You will join a collaborative supervisory team at UEA (Andrea Münsterberg, Tim Grocott, James Mccoll), gaining skills in developmental biology, molecular genetics, live imaging/microscopy, and computational biology. This multi-disciplinary project offers the opportunity to make fundamental discoveries about the molecular control of heart development.

Contact a.munsterberg@uea.ac.uk or t.grocott@uea.ac.uk for more information.

The Norwich Research Park Biosciences Doctoral Training Programme (NRPDTP) is offering fully funded studentships for October 2027 entry. The programme offers postgraduates the opportunity to undertake a 4-year PhD research project whilst enhancing professional development and research skills through a comprehensive training programme. You will join a vibrant community of world-leading researchers. All NRPDTP students undertake a three-month professional internship placement (PIPS) during their study. The placement offers exciting and invaluable work experience designed to enhance professional development. Full support and advice will be provided by our Professional Internship team.

This project has been shortlisted for funding by the NRPDTP. Shortlisted applicants will be interviewed on the 2nd, 3rd and 4th February 2027.

This project is awarded with a 4-year Norwich Research Park Biosciences Doctoral Training Partnership PhD DTP studentship. The studentship includes payment of tuition fees (directly to the University), a stipend to cover living expenses (2026/27 stipend rate: £21,805, and a Research Training Support Grant of £5,000pa for each year of the studentship.

Our partners value diverse and inclusive work environments that are positive and supportive. Students are selected for admission without regard to gender, marital or civil partnership status, disability, race, nationality, ethnic origin, religion or belief, sexual orientation, age or social background.

To maximise accessibility and attract students from underrepresented groups to our programme we have introduced bespoke templates for applicant Personal and Research statements which will enable every applicant to fully represent themselves through providing suitable examples and evidence. These forms are on the NRPDTP website and must be used for these sections of the application form.

Entry requirements

At least UK equivalence Bachelors (Honours) 2:1. English Language requirement (Faculty of Science equivalent: IELTS 6.5 overall, 6 in each category).

Mode of study

Full-time

Start date

1 October 2027

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