工程生物学解码侧根起始基因调控网络博士研究员
PhD Studentship: Engineering Biology to Decode Gene Regulatory Networks in Lateral Root Initiation
原帖优先：申请材料、截止时间与资格以原帖和学校官方说明为准。
AI 中文速览
- 研究内容
- 本项目旨在利用基于丝氨酸整合酶的DNA记录器并结合单细胞RNA测序技术，在拟南芥中构建和优化遗传回路，以高时空分辨率重建和解析侧根祖细胞特异化过程中的基因表达程序与调控网络。
- 申请条件
- 要求申请者为有上进心的本科毕业生，对工程生物学和植物科学充满热情，并具备发展批判性思维和科学独立性的潜力。
- 待遇
- 提供为期4年的Norwich Research Park Biosciences Doctoral Training Partnership (NRPDTP) 博士奖学金，涵盖大学学费、2026/27学年每年21,805英镑的生活津贴，以及每年5,000英镑的研究培训支持补助金（RTSG）。
- 申请方式
- 原文未说明具体申请方式与截止日期，请参考相关博士培训合作伙伴项目（DTP）的官方申请渠道。
由 gemini-2.5-flash-lite 生成，博士岗判定置信度 100%。
岗位信息
- 截止
- （Europe/London） 剩 36 天
- 学科
- 农业与生物科学
- 合同类型
- 雇佣合同
- 原文薪资
- GBP 21,805 / 年（税前）
- 税后月薪（估）
- ¥13,700；房租后 ¥5,400
- 估算假设
- 单身、无子女、雇佣合同的粗略估算，以学校 offer 为准；扣除率 18%；汇率日期 2026-10-01
- 原帖发布
- 本站收录
- 内容更新
- 原帖导师候选（待核验）
- Guiziou
- 来源
- jobs.ac.uk（英国博士项目及学术招聘） · 最近核对 2026-10-24
- 详情核验
判定依据（原文摘录）
- 这是一个博士培养机会
We’re offering an exciting PhD opportunity with the Guiziou Group at the Earlham Institute
- 招收对象包含本科毕业生且工作语言为英语
Are you a motivated undergraduate with a passion for engineering biology and plant science?
原文
Are you a motivated undergraduate with a passion for engineering biology and plant science?
We’re offering an exciting PhD opportunity with the Guiziou Group at the Earlham Institute using engineering biology and single-cell genomic technology to drive forward our understanding of lateral root initiation.
This PhD project aims to use DNA-based recorders (based on serine integrase) to reconstruct the gene expression programme during lateral root founder cell specification. You will combine this cutting-edge methodology with single-cell RNA sequencing to dissect spatiotemporal gene regulation of lateral root initiation.
You will build and optimise integrase-based genetic circuits in Arabidopsis to record the order in which genes of interest are expressed. Using fluorescence microscopy, you will analyse the resulting Arabidopsis lines to better understand the gene regulatory network underlying lateral root founder cell specification, with high spatiotemporal resolution.
You will also use single-cell RNA sequencing (combined with FACS) to determine the cell state of precise lateral root founder cell subpopulations marked with the engineered genetic circuit. During this project, you will develop your critical thinking and scientific independence, with the final part of the project being up to you to shape.
This project offers:
• Comprehensive training in engineering biology, automation, molecular biology, microscopy, plant transformation, protoplasting, FACS, single-cell RNA sequencing and analysis.
• Opportunities to present your work at international conferences and industry symposia.
• A vibrant, supportive research environment with excellent career progression: past students at the Earlham Institute became biotech CEOs, group leaders, and research scientists.
• A highly collaborative and supportive research community with access to training and career development opportunities across the Norwich Research Park.
You will become an expert in plant engineering biology through this project and take part in the mission of the Guiziou group, which is to have a tangible impact on sustainable agriculture.
This project is awarded with a 4-year Norwich Research Park Biosciences Doctoral Training Partnership PhD DTP studentship. The studentship includes payment of tuition fees (directly to the University), a stipend to cover living expenses (2026/27 stipend rate: £21,805, and a Research Training Support Grant of £5,000pa for each year of the studentship.