西方生活方式对肠道微生物组进化与生态影响博士研究员

PhD Studentship: Evolutionary and Ecological Impact of the Western Lifestyle on the Gut Microbiome

The University of East Anglia · 英国 · Norwich

原帖优先:申请材料、截止时间与资格以原帖和学校官方说明为准。

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研究内容
本项目将探索西方生活方式如何影响肠道细菌的生态与进化,利用超过6,000个肠道宏基因组和最先进的菌株级宏基因组学技术,识别工业化相关的生态与进化特征,确定细菌群体随时间、宿主和环境的适应规律,并重建细菌代谢位点并研究其全球变异。
申请条件
申请者需具备相关背景,曾接触统计学或编程会有所帮助,但专业方法将通过指导和协作进行教授。
待遇
提供为期4年的Norwich Research Park Biosciences Doctoral Training Partnership (DTP) 博士奖学金,包含直接支付给大学的学费、用于生活开销的津贴(2026/27学年津贴标准为每年21,805英镑),以及每年5,000英镑的研究与培训支持津贴(RTSG)。
申请方式
原文未说明具体的申请方式与截止日期,请参考相关DTP项目的官方申请通道。

由 gemini-2.5-flash-lite 生成,博士岗判定置信度 100%。

岗位信息

截止
(Europe/London) 剩 36 天
学科
生物化学、遗传与分子生物学
合同类型
雇佣合同
原文薪资
GBP 21,805 / 年(税前)
税后月薪(估)
¥13,700;房租后 ¥5,400
估算假设
单身、无子女、雇佣合同的粗略估算,以学校 offer 为准;扣除率 18%;汇率日期 2026-10-01
原帖发布
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内容更新
原帖导师候选(待核验)
Prof Falk Hildebrand, Dr Wilfried Haerty
来源
jobs.ac.uk(英国博士项目及学术招聘) · 最近核对 2026-10-24
详情核验
判定依据(原文摘录)
  • 这是一项博士培养机会
    This PhD will explore how Western lifestyles affect the ecology and evolution of gut bacteria.
  • 工作/研究语言为英语
    During this 4-year DTP programme, you will join an interdisciplinary research environment spanning microbial ecology, evolutionary genomics and bioinformatics.
  • 奖学金及资助类型
    This project is awarded with a 4-year Norwich Research Park Biosciences Doctoral Training Partnership PhD DTP studentship.
原文

The human gut microbiome is a complex ecosystem shaped by diet, the host and microbial transmission between people. While gut bacterial populations were once thought to be genetically stable, we now know that they can evolve within their hosts over remarkably short timescales. Our research shows that Westernised and less-industrialised populations differ substantially in gut bacterial composition, diversity, microbial sharing and evolutionary patterns, with potential consequences for microbiome resilience and human health.

This PhD will explore how Western lifestyles affect the ecology and evolution of gut bacteria. Using more than 6,000 gut metagenomes and state-of-the-art strain-resolved metagenomics, you will:

• Identify ecological and evolutionary signatures associated with industrialisation

• Determine how bacterial populations adapt over time, hosts and environments

• Reconstruct bacterial metabolic niches and investigate how these vary globally

You will gain advanced training in evolutionary theory, microbial ecology, high-resolution metagenomics, sequencing technologies, statistics and computational analysis. Previous exposure to statistics or programming is useful, but specialist methods will be taught through mentorship and collaboration.

During this 4-year DTP programme, you will join an interdisciplinary research environment spanning microbial ecology, evolutionary genomics and bioinformatics. Opportunities include a research visit with collaborators in Poland, international conferences and training courses, and a 3-month industrial placement. The project offers strong publication opportunities and substantial scope to develop your own research questions and scientific direction.

The project is supervised by Prof Falk Hildebrand ( https://www.falk.science ), Dr Wilfried Haerty ( https://www.earlham.ac.uk/profile/wilfried-haerty ) based at the Quadram and Earlham Institutes at Norwich Research Park. The team provides complementary expertise in microbial ecology, evolutionary genomics, computational biology and microbial physiology.

Norwich is a compact historic city with a vibrant research and student community, an active independent food, pub and coffee scene, and easy access to the Norfolk countryside and coast.

This project is awarded with a 4-year Norwich Research Park Biosciences Doctoral Training Partnership PhD DTP studentship. The studentship includes payment of tuition fees (directly to the University), a stipend to cover living expenses (2026/27 stipend rate: £21,805, and a Research Training Support Grant of £5,000pa for each year of the studentship.

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