小分子和基于肽的放射性缀合物安全性评估综合临床前管线开发博士研究员

AstraZeneca Non-Clinical PhD Studentship in Development of an Integrated Pre-Clinical Pipeline for Safety Assessment of Small Molecule and Peptide-Based Radioconjugates

The Chancellor, Masters, and Scholars of the University of Cambridge · 英国

原帖优先:申请材料、截止时间与资格以原帖和学校官方说明为准。

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研究内容
本项目旨在利用体内PET成像和多模态离体组织分析技术,建立一个小分子和基于肽的放射性缀合物安全性评估的综合临床前框架,开发用于评估下一代放射性药物安全性的创新方法。
申请条件
申请人应拥有或即将获得英国大学的一等或高2:1学士学位,或海外大学同等标准的学位,专业方向为影像学、生物学、生物化学、化学、生物医学科学、制药科学、数据分析或医学等相关学科,能够在一个多学科研究环境中独立思考和工作。
待遇
资助期限为4年,涵盖学生的生活津贴(stipend)以及Home标准的学费。
申请方式
申请截止日期为2026年10月5日星期五。申请应通过剑桥大学申请门户网站提交,选择放射学博士(PhD in Radiology)课程,并将此奖学金标题作为拟议的项目标题,同时在申请中注明参考编号RQ51135。
材料清单
  • 一页A4纸的陈述文件,包含申请该奖学金的动机、相关技能、若被录用希望取得的成果以及长期职业抱负(代替研究计划书上传)

由 gemini-2.5-flash-lite 生成,博士岗判定置信度 100%。

岗位信息

截止
原帖未给出
学科
药理、毒理与药剂学
合同类型
奖学金
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内容更新
导师
Luigi Aloj
来源
The Chancellor, Masters, and Scholars of the University of Cambridge 官方招聘 · 最近核对 2026-10-10
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判定依据(原文摘录)
  • 这是一项博士培养机会
    Applications are invited for an AstraZeneca Non-Clinical PhD Studentship in Development of an Integrated Pre-Clinical Pipeline for Safety Assessment of Small Molecule and Peptide-Based Radioconjugates Using In Vivo PET Imaging and Multimodal Ex Vivo Tissue Analysis.
  • 英语要求(英国高校通用标准)
    Applications should be made via the University Application portal.
原文

Applications are invited for an AstraZeneca Non-Clinical PhD Studentship in Development of an Integrated Pre-Clinical Pipeline for Safety Assessment of Small Molecule and Peptide-Based Radioconjugates Using In Vivo PET Imaging and Multimodal Ex Vivo Tissue Analysis.

The Department of Radiology at the University of Cambridge, in partnership with AstraZeneca, is offering a funded PhD studentship to develop innovative approaches for the safety assessment of next-generation radiopharmaceuticals. We are seeking a motivated, enthusiastic and inquisitive student with an interest in molecular imaging, radiopharmaceutical sciences, oncology, translational medicine and drug development. The successful candidate will join a highly multidisciplinary team, supervised by Professor Luigi Aloj (Department of Radiology), Dr Flaviu Bulat (Department of Radiology), Dr Nisha Kuzhuppilly Ramakrishnan (Department of Clinical Neurosciences), and Dr Andreas Dannhorn (AstraZeneca), and gain experience working across both academic and industrial research environments. For the full details of this studentship, please see the Student Funding Portal here

Project Aims:

Targeted radionuclide therapy is an emerging and highly promising approach for cancer treatment. Radioconjugates combine tumour-targeting molecules with therapeutic radioisotopes, enabling the selective delivery of radiation to cancer cells while minimising damage to healthy tissue. Despite recent clinical successes, there remains a significant need for improved methods to evaluate how these compounds distribute throughout the body and to better understand potential toxicities in normal organs. This project aims to establish an integrated preclinical framework for the assessment of small molecule and peptide-based radioconjugates using advanced molecular imaging and tissue analysis techniques. Additional details about the project can be found on the Student Funding Portal here - https://www.student-funding.cam.ac.uk/fund/development-of-an-integrated-pre-clinical-pipeline-for-safety-assessment-of-small-molecule-and-peptide-based-radioconjugates-using-in-vivo-pet-imaging-and-multimodal-ex-vivo-tissue-analysis-2026

Candidate:

We are seeking a highly motivated and enthusiastic individual capable of thinking and working independently within a multidisciplinary research environment. Applicants should have or shortly expect to obtain a first or high 2:1 bachelor's degree from a UK university, or an equivalent standard from an overseas university, in a relevant subject such as imaging, biology, biochemistry, chemistry, biomedical sciences, pharmaceutical sciences, data analysis, or medicine.

Funding:

The funding for this post is available for 4 years. Funding will cover the student's stipend and tuition fees at the Home rate. This studentship is also open to overseas students who meet the UK residency requirements (home fees) or who can cover the extra costs associated with international student fees through scholarships or funding schemes. Students may not supplement fees via self funding.

How to Apply:

The deadline for applications is Friday 30th October 2026.

Applications should be made via the University Application portal. When asked to select a course, please apply for the PhD in Radiology. You should then put the title of this studentship as your proposed project title. You are not required to write your own research proposal. When asked for a research proposal in the applicant portal, instead please upload one side of A4 with your motivation for applying for the studentship, your relevant skills, what you hope to achieve if appointed, and long-term career aspirations. You do not need to secure a supervisor before applying for this studentship.

Informal enquiries about the project are welcome and should be directed to Professor Luigi Aloj: la398@medschl.cam.ac.uk

For application process queries, please contact clusterPG@medschl.cam.ac.uk .

Please quote reference RQ51135 on your application and in any correspondence about this vacancy.

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

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