利用疟原虫蛋白质降解机制对抗自身的博士研究员
PhD Studentship (Fixed Term)
原帖优先：申请材料、截止时间与资格以原帖和学校官方说明为准。
AI 中文速览
- 研究内容
- 本项目将结合寄生虫遗传学、生物化学和化学生物学，探索利用疟原虫自身的蛋白质降解机制选择性破坏其生存所需蛋白质的全新抗疟药物开发策略。
- 申请条件
- 申请人应持有（或预计取得）相关学科本科荣誉学位或硕士学位的英国二等一（upper 2.1）或更高同等学历，且必须符合英国本地费用（Home fees）资格，并在面试前满足学校的语言要求。
- 待遇
- 提供从2027年10月起为期4年的全额资助，涵盖按当前研究委员会标准的学生生活津贴（stipend）以及英国本地大学学费（Home University Fees）。
- 申请方式
- 所有申请均须通过剑桥大学申请者门户网站在线提交攻读病理学博士学位（BLPA22）的申请，申请时需注明参考编号 PK49372 或 PK51394，截止日期为 2026年12月2日。
- 材料清单
- 2 份学术推荐信
- 阐述申请该领域博士动机、研究兴趣、背景以及个人优势与经验的材料（具体通过学校申请门户提交）
由 gemini-2.5-flash-lite 生成，博士岗判定置信度 100%。
岗位信息
- 截止
- 原帖未给出
- 学科
- 生物化学、遗传与分子生物学
- 合同类型
- 奖学金
- 本站收录
- 内容更新
- 原帖导师候选（待核验）
- Katerina Artavanis-Tsakonas, Laura Itzhaki
- 来源
- The Chancellor, Masters, and Scholars of the University of Cambridge 官方招聘 · 最近核对 2026-10-17
判定依据（原文摘录）
- 这是一项博士培养机会
All applications should be made online via the University's Applicant Portal for a PhD in Pathology (BLPA22).
- 英语要求可通过满足学校常规博士语言要求达成
the Department requires that by the time of interview all potential students must have fulfilled the language requirements for admission.
- 仅限英国本地学费资格申请者
The studentships are available to students who qualify for UK HOME FEES ONLY .
原文
Project Title: Turning the Malaria Parasite's Protein Degradation Machinery Against It -Professor Katerina Artavanis-Tsakonas, co-supervised with Laura Itzhaki (Department of Pharmacology)
Malaria remains a major global health challenge, with drug resistance threatening the effectiveness of existing treatments. This project will explore a fundamentally different way to kill malaria parasites: harnessing their own protein-degradation machinery to selectively destroy proteins they need to survive. Our lab studies how the ubiquitin system works in Plasmodium falciparum, revealing important differences between parasite and human cells that could be exploited therapeutically. This project will combine parasite genetics, biochemistry and chemical biology to develop new ways of manipulating protein stability. The aim is to create powerful tools for discovering new parasite biology while exploring novel strategies for antimalarial drug development.
The Department of Pathology has an excellent reputation in pure biological and biomedical research and is offering fully funded* studentships from October 2027 to work with one of the Research Group Leaders in this large and vibrant Department.
All applications should be made online via the University's Applicant Portal for a PhD in Pathology (BLPA22). A completed application must be submitted by the closing date below. An application is only complete when all supporting documents, including the 2 academic references, are submitted.
It is the applicant's responsibility to ensure their referees submit their references before the closing date of the studentship.
The studentships are available to students who qualify for UK HOME FEES ONLY .
Please check for eligibility details using this website: https://www.postgraduate.study.cam.ac.uk/finance/fees/what-my-fee-status
Funding will cover the student's stipend at the current Research Council rate and Home University Fees. The studentship will be funded for 4 years from October 2027.
Applicants should hold (or expect to obtain) the equivalent of a UK upper 2.1 or higher in an undergraduate honours or Masters degree in a relevant subject. The studentship is open to those eligible for the Home rate of University fees. Additionally, the Department requires that by the time of interview all potential students must have fulfilled the language requirements for admission. ( http://www.graduate.study.cam.ac.uk/courses/directory/blpapdpth/requirements )
Please also explain your motivation why you wish to pursue a PhD in this area, outline your research interests and background, and describe the qualities and experience you will bring to the role.
Applications from ineligible candidates will not be considered.
Further information about the course can be found here.
Closing date: 2nd December 2026
Please quote reference PK49372 on your application and in any correspondence about this vacancy.
Please quote reference PK51394 on your application and in any correspondence about this vacancy.
The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.
The University has a responsibility to ensure that all employees are eligible to live and work in the UK.