巴雷特食管进展风险建模博士研究员

Richard Elphick Studentship in Modelling progression risks in Barrett's oesophagus.

The Chancellor, Masters, and Scholars of the University of Cambridge · 英国

原帖优先:申请材料、截止时间与资格以原帖和学校官方说明为准。

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研究内容
本项目将利用大型多中心数据集开发巴雷特食管进展的马尔可夫多状态模型,估计转移风险并纳入患者及疾病因素来预测个体癌症风险并个性化监测间隔;通过微观模拟研究比较固定与基于风险的监测策略,并评估内窥镜与基于海绵胶囊(Cytosponge)方法的优劣,最终转化为临床决策支持与可视化工具。
申请条件
申请者需满足肿瘤学博士(PhD in Oncology)的入学要求,欢迎英国本土及海外申请者申请。
待遇
提供3.5年的全额资助,包括英国本土或海外标准的学费、适用的UKRI标准生活津贴(maintenance stipend)以及研究补助金(research emolument),将于2027-28学年开始。
申请方式
申请人须通过大学申请门户网站(Applicant Portal)申请肿瘤学博士,在申请表相关部分填入项目标题及导师姓名,在申请中选择“Yes - I wish to be considered for funding”并从可用资助机会列表中选择理查德·埃尔菲克学生奖学金(Richard Elphick Studentship),并建议将三一学院(Trinity)列为第一志愿学院,申请时请注明参考编号 RD51277。
材料清单
  • 动机信(statement of interest)
  • 空白文档(在指定的研究所需提案部分上传以满足系统要求,本项目不需要研究提案)

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岗位信息

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导师
Professor Rebecca Fitzgerald, Professor Nora Pashayan
来源
The Chancellor, Masters, and Scholars of the University of Cambridge 官方招聘 · 最近核对 2026-10-10
详情核验
判定依据(原文摘录)
  • 这是一项博士培养机会
    Applications are invited for the Richard Elphick Studentship, a fully funded PhD studentship at Trinity College
  • 明确了导师姓名
    under the supervision of Professor Rebecca Fitzgerald (Department of Oncology) and Professor Nora Pashayan (Department of Public Health and Primary Care).
  • 国际学生可申请且提供全额资助
    Applications are welcomed from UK and Overseas candidates who meet the entry requirements for the PhD in Oncology. The studentship will commence in the 2027-28 academic year and will provide full funding for 3.5 years
原文

Applications are invited for the Richard Elphick Studentship, a fully funded PhD studentship at Trinity College, established by friends and family in memory of Richard. The successful candidate will undertake research on "Modelling progression risks in Barrett's oesophagus" under the supervision of Professor Rebecca Fitzgerald (Department of Oncology) and Professor Nora Pashayan (Department of Public Health and Primary Care).

This is an opportunity to work with Professor Fitzgerald and her research group, who are internationally renowned for their work on Barrett's oesophagus including the development of a novel, non-endoscopic capsule sponge test, and Professor Pashayan's research group who are leading in quantitative methods to develop risk-based approaches to cancer screening.

Project Outline:

Oesophageal adenocarcinoma (OAC), the most common oesophageal cancer in the UK and US, has a 5-year survival rate below 20%, though outcomes improve with early detection. Barrett's oesophagus, an asymptomatic precursor, is monitored to detect and treat dysplasia before cancer develops or to identify cancer at an earlier stage. However, most cases remain undiagnosed. The Cytosponge, developed by Prof Fitzgerald's lab, offers a cheaper, GP-based alternative to endoscopy, increasing Barrett's detection and the number of people entering surveillance.

This project will use large multicentre datasets to develop a Markov multistate model of Barrett's oesophagus progression, estimating transition risks and incorporating patient and disease factors to predict individual cancer risk and personalise surveillance intervals.

Microsimulation studies will compare fixed and risk-based surveillance strategies and evaluate endoscopy versus Cytosponge-based approaches. Findings will be translated into a clinical decision-support and visualisation tool that communicates personalised progression risk and supports tailored surveillance recommendations for patients and clinicians.

Eligibility and Funding:

Applications are welcomed from UK and Overseas candidates who meet the entry requirements for the PhD in Oncology.

The studentship will commence in the 2027-28 academic year and will provide full funding for 3.5 years, including tuition fees at either the UK Home or Overseas rate, a maintenance stipend at the applicable UKRI rate, and a research emolument. More details of the funding amounts can be found on the University's postgraduate funding webpages and the Trinity College website.

How to Apply

Applicants should apply for the PhD in Oncology via the University's Applicant Portal and enter the project title and supervisor(s)' names in the relevant section of the application form. In their statement of interest, applicants should demonstrate how their skills align with the requirements of the project. A research proposal is not required for this application; however, to satisfy system requirements, applicants should upload a blank document in the designated research proposal section. Applicants must select "Yes - I wish to be considered for funding" within the application and choose the Richard Elphick Studentship from the list of available funding opportunities and complete any additional questions.

Applicants are advised to indicate Trinity as the College of first preference on their application to the University.

Further Information

Enquiries regarding the research project, application process or the PhD in Oncology should be directed to the Postgraduate Administration Team, Department of Oncology (email: postgradadmin@oncology.cam.ac.uk )

Enquiries relating to the Richard Elphick Studentship should be directed to Trinity College (email: gradfunding@trin.cam.ac.uk ).

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society. The University has a responsibility to ensure that all employees are eligible to live and work in the UK

Please quote reference RD51277 on your application and in any correspondence about this vacancy.

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

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