利用超声波喷雾干燥制备下一代颗粒药物博士研究员
Next-generation granular pharmaceuticals via ultrasonic spray drying
原帖优先：申请材料、截止时间与资格以原帖和学校官方说明为准。
博士招生与资助公告
- 申请年度
- 2027；原帖说明：How to apply Apply now You need to: • choose programme type (Research), 2027/28, Faculty of Engineering and Physical Sciences • select Full time or Part time • search for programme PhD Chemical Engineering (6939) • add name of the supervisor in section 2 of the application Applications should include: • your CV (resumé) • 2 academic references • degree transcripts and certificates to date • English language qualification (if applicable)
- 最近申请截止
- 2027-06-30
- 全部申请截止
- （Europe/London）
- 资助原文
- Fees and funding We offer a range of funding opportunities for both UK and international students. Horizon Europe fee waivers automatically cover the difference between overseas and UK fees for qualifying students. Competition-based Presidential Bursaries from the University cover the difference between overseas and UK fees for top-ranked applicants. Competition-based studentships offered by our schools typically cover UK-level tuition fees and a stipend for living costs for top-ranked applicants. Funding will be awarded on a rolling basis, so apply early for the best opportunity to be considered. For more information, please visit our postgraduate research funding pages.
- 资助条件
- 原帖为竞争性或附条件资助说明，未确认本项目获资助及申请人能获奖；不作为保证全奖。
- 原帖材料说明
- • your CV (resumé)
- • 2 academic references
- • degree transcripts and certificates to date
- • English language qualification (if applicable)
确定性信息来自对应版本的完整原帖。原帖只提供日期，日末和学校当地时区为本站转换假设。筛选使用最后申请截止；资助与录取以学校审核结果为准。
AI 中文速览
- 研究内容
- 本项目将研究如何利用超声波生产更均匀、稳定且高质量的颗粒状药物粉末，同时降低能耗。通过结合实验研究、先进颗粒表征和过程建模，该工作将实现更高效、可扩展的药物制造。
- 申请条件
- 申请人必须拥有英国 2:1 荣誉学位或同等国际学历，专业背景包括化学工程、制药工程、药学、化学、材料科学、机械工程或紧密相关的学科。必备技能包括对制药制造、颗粒工程、喷雾干燥、雾化或相关过程技术有浓厚兴趣，具备良好的分析和问题解决能力，能够开展实验研究并解释科学数据。
- 待遇
- 提供针对英国和国际学生的多种资助机会，包括地平线欧洲学费减免、竞争性的校长奖学金（Presidential Bursaries）以及通常涵盖英国本土学费和生活费津贴的院系竞争性奖学金。资助以滚动方式发放，建议尽早申请。
- 申请方式
- 申请人需选择研究型项目类型（2027/28学年，工程与物理科学学院），选择全日制或非全日制，搜索“PhD Chemical Engineering (6939)”项目，并在申请表的第二部分添加导师姓名后通过网申系统提交。
- 材料清单
- 个人简历（CV）
- 2封学术推荐信
- 至今的学位成绩单和证书
- 英语语言资格证明（如适用）
由 gemini-2.5-flash-lite 生成，博士岗判定置信度 100%。
岗位信息
- 最终轮次截止
- 2027-06-30
- 学科
- 化学工程
- 合同类型
- 项目资助
- 本站收录
- 内容更新
- 导师
- Dr Xi Yu
- 来源
- 南安普顿大学博士研究项目招生 · 最近核对 2026-10-10
- 详情核验
判定依据（原文摘录）
- 这是一项博士培养机会
Type of degree Doctor of Philosophy
- 入学要求持有2:1荣誉学位及相关背景
You must have a UK 2:1 honours degree or its international equivalent, in one of the following: • chemical engineering • pharmaceutical engineering • pharmacy • chemistry • materials science • mechanical engineering • a closely related discipline
原文
View all current projects
Postgraduate research project
Next-generation granular pharmaceuticals via ultrasonic spray drying
Funding
Competition funded
Competition funded
View fees and funding
Type of degree
Doctor of Philosophy
Entry requirements
2:1 honours degree
2:1 honours degree
View full entry requirements
Faculty graduate school
Faculty of Engineering and Physical Sciences
Closing date
30 Jun 2027
On this page
About the project
Potential supervisors
Entry requirements
Fees and funding
How to apply
Contact us
About the project
Potential supervisors
Entry requirements
Fees and funding
How to apply
Contact us
About the project
This project will investigate how ultrasound can produce more uniform, stable and high-quality granular pharmaceutical powders while reducing energy use. Combining experimental research, advanced particle characterisation and process modelling, the work will enable more efficient, scalable drug manufacturing.
The pharmaceutical industry increasingly requires manufacturing technologies that can deliver powders with tightly controlled particle size, morphology, flowability and dissolution performance, while maintaining product stability and reducing energy consumption. Conventional spray drying, particularly using two-fluid nozzles, can provide limited control over droplet size and particle characteristics and may expose heat-sensitive pharmaceutical materials to undesirable thermal and shear stresses.
This project will develop an innovative spray drying system incorporating ultrasonic atomisation to produce granular pharmaceutical powders with improved and more consistent properties. Ultrasonic atomisation uses high-frequency sound waves to generate fine droplets with controlled size, offering a promising route to improved atomisation efficiency, reduced shear and lower energy consumption. The research will establish the relationships between key processing parameters, including ultrasonic frequency, feed concentration, drying temperature and airflow rate, and the resulting particle characteristics, including size, morphology, density, flowability, compressibility and dissolution behaviour.
The project will combine experimental investigation, process optimisation and modelling to develop a validated understanding of the mechanisms governing ultrasonic atomisation and spray drying. Advanced characterisation techniques, including scanning electron microscopy (SEM) and laser diffraction, will be used to evaluate particle properties and support process–structure–performance relationships.
Expected outcomes include an optimised and scalable ultrasonic spray drying process, a validated process model, mechanistic understanding of ultrasound-assisted atomisation and prototype granular pharmaceutical formulations. The research will provide valuable training in pharmaceutical processing, particle engineering, experimental design, advanced characterisation and process modelling, while addressing an important industrial challenge in the manufacture of high-quality pharmaceutical powders and drug delivery systems.
The School of Chemistry and Chemical Engineering is committed to promoting equality, diversity inclusivity as demonstrated by our Athena SWAN award. We welcome all applicants regardless of their gender, ethnicity, disability, sexual orientation or age, and will give full consideration to applicants seeking flexible working patterns and those who have taken a career break. The University has a generous maternity policy, onsite childcare facilities, and offers a range of benefits to help ensure employees’ well-being and work-life balance. The University of Southampton is committed to sustainability and has been awarded the Platinum EcoAward.
Potential supervisors
Lead supervisor
Dr Xi Yu
Lecturer in Chemical Engineering
Research interests
• Low carbon fuels
• Granulation and tableting
• Computational fluid dynamics
Supervisors
Dr Xuan Li
PhD
Lecturer B in Mechanical Engineering
Research interests
• Novel miniature ultrasonic surgical device design
• Ultrasonically assisted machining and manufacturing
• New generation of piezoelectric materials
Entry requirements
You must have a UK 2:1 honours degree or its international equivalent, in one of the following:
• chemical engineering
• pharmaceutical engineering
• pharmacy
• chemistry
• materials science
• mechanical engineering
• a closely related discipline
Essential skills:
• strong interest in pharmaceutical manufacturing, particle engineering, spray drying, atomisation, or related process technologies
• good analytical and problem-solving skills, with an ability to undertake experimental research and interpret scientific data
Fees and funding
We offer a range of funding opportunities for both UK and international students. Horizon Europe fee waivers automatically cover the difference between overseas and UK fees for qualifying students.
Competition-based Presidential Bursaries from the University cover the difference between overseas and UK fees for top-ranked applicants.
Competition-based studentships offered by our schools typically cover UK-level tuition fees and a stipend for living costs for top-ranked applicants.
Funding will be awarded on a rolling basis, so apply early for the best opportunity to be considered.
For more information, please visit our postgraduate research funding pages.
How to apply
Apply now
You need to:
• choose programme type (Research), 2027/28, Faculty of Engineering and Physical Sciences
• select Full time or Part time
• search for programme PhD Chemical Engineering (6939)
• add name of the supervisor in section 2 of the application
Applications should include:
• your CV (resumé)
• 2 academic references
• degree transcripts and certificates to date
• English language qualification (if applicable)
Contact us
Faculty of Engineering and Physical Sciences
If you have a general question, email our Doctoral College (doctoralcollege-admissions@soton.ac.uk).
Project leader
For an initial conversation, email Dr Xi Yu (Xi.Yu@soton.ac.uk).